SBRI19001U Translational Discovery Omics I - Genomics, Epigenomics, and Transcriptomics
BRIDGE - Translational Excellence Programme
The aim of the course is to provide the participants with:
i) an overview of the theory and application of technologies in genetic research of health and disease
ii) an introduction to the role of genetics in elucidating disease mechanisms and inferring causality, and
iii) an understanding of the application of technologies in epigenomic and transcriptomic research.
The main themes covered in the course include:
- Phenotype definition
- Genetic variation in health and disease
- Methods in genome research including genome sequencing
- Analytical methods in genome research
- Methods and applications of epigenetic research
- Transcriptomic methods and applications
This course is primarily focused on basic omics research. Translational research applications of omics are included in the later omics courses in the BRIDGE Programme.
Upon completing the course, participants should be able to:
Knowledge
- Demonstrate an understanding of how genetic variation impacts health and disease.
- Discuss the applications of contemporary methodologies to study genetic variation.
- Have an awareness of the strengths and limitations of genetic variation in elucidating disease mechanisms and inferring causality.
- Gain an understanding of the principles and applications of epigenomic and transcriptomic profiling of tissues and single cells.
Skills
- Critically evaluate the results from studies of human genetic variation.
- Apply basic tools to study relationships among individuals and populations using genetic data.
- Develop an appropriate design for a genetic study of a human disease.
Competences
- Understand the central concepts of genomics, epigenomics and transcriptomics, and be able to engage in informed discussions about related topics with peers, clinicians, and the public.
Course literature will be published on Absalon.
The course will end with an evaluation where participants must reflect on course learning outcomes and give feedback for course development.
- Category
- Hours
- Lectures
- 12.5
- Class Instruction
- 5
- Preparation
- 3
- Theory exercises
- 3.5
- Total
- 24.0
The BRIDGE – Translational Excellence Programme offers to a few selected graduated PhDs
- a two-year postdoctoral fellowship in translational medicine (BRIDGE Programme).
- a package of three courses in Translational Discovery Omics (BRIDGE Omics Programme).
This course is only available to graduated PhDs enrolled in either of the programmes. Fellows and participants enrolled in the programmes are automatically enrolled in this course upon admission to one of the programmes.
For further information about the BRIDGE Programme, please go to the website: www.bridge.ku.dk
For further information about the Omics Programme, please go to the website: www.bridge.ku.dk/about/academic-curriculum/bridgeomics/
- Credit
- 0 ECTS
- Type of assessment
- Continuous assessmentRequirement to attend classes
- Type of assessment details
- Attendance and active participation.
- Exam registration requirements
Participants are automatically registered for the examination upon admission to the BRIDGE - Translational Excellence Programme (Fellowship or BRIDGE Omics Programme).
- Aid
- All aids allowed
- Marking scale
- passed/not passed
- Censorship form
- No external censorship
Criteria for exam assesment
Active contribution and course participation according to the BRIDGE Guidelines and Practicalities.
Course information
- Language
- English
- Course code
- SBRI19001U
- Credit
- 0 ECTS
- Level
- Part Time MasterPh.D.
- Placement
- Autumn
- Schedule
- See course dates and course programme in Absalon.
- Course capacity
- 20 participants
Study board
- Study Board for the Professionel Master´s Degree Programmes at The Faculty og Health and Medical Science
Contracting department
- The Novo Nordisk Foundation Center for Basic Metabolic Research
Contracting faculty
- Faculty of Health and Medical Sciences
Course Coordinators
- Tuomas Oskari Kilpeläinen (tuomas.kilpelainen@sund.ku.dk)
- Laura Maarit Pikkupeura (laura.pikkupeura@sund.ku.dk)
- Mette Andersen Lepola (Metteandersen@sund.ku.dk)
- Torben Hansen (torben.hansen@sund.ku.dk)