SMOK15001U Molecular Pathology
MSc Programme in Molecular Biomedicine
The focus of the course is the study of disease, including the cause (etiology), mechanisms of development (pathogenesis), and structural/functional alterations involved. The course begins with an introduction to the normal histology of relevant tissues and organs, required to later identify pathological lesions. Then the pathologic basis of a broad range of common diseases is covered. Main topics include cell injury, adaptation, and death; inflammation; neoplasia; and cardiovascular, immunological, infectious, neurological, metabolic, and musculoskeletal diseases. There is a focus on definitions, terminology, and the description of morphological changes in cells and tissues, as illustrated by clinical examples. There is a strong emphasis on current pathophysiological theories and molecular disease mechanisms, which will be covered by lectures and critically discussed during student activating journal clubs.
The student will acquire a broad understanding of pathologic concepts and a profound knowledge of the most common diseases and their underlying mechanisms.
The successful student will know the normal histology of most tissues and organs, be able to recognize and describe relevant pathologic morphologic alterations at the microscopic level, and understand important functional consequence. The student will be familiar with the pathologic terminology, and should know and be able to describe the current pathophysiologic theories and molecular mechanisms related to the development of the included diseases.
The course should provide the student the theoretical foundation required to engage in critical reading and discussion of disease mechanisms and the capacity to relate basic knowledge to more clinical aspects of the relevant diseases.
Recommended textbooks are Robbins & Cotran: Pathologic Basis of Disease, 9th Ed. and Ross & Pawlina: Histology – A Text and Atlas 7th Ed. (or any similar histology book).
Case material and original articles discussed at journal clubs.
Suggested readings will be available on Absalon.
12 microscopy lessons in normal histology (SAU24)
14 microscopy lessons in pathology (SAU24)
16 CASE lessons (8 x 2 lessons, SAU24)
12 journal clubs (6 x 2 lessons, SAU24)
2 lessons related to exam preparation
- Class Instruction
- Exam Preparation
Open for credit transfer students. Apply here:
- 15 ECTS
- Type of assessment
- Written examination, 4 hours under invigilation---
- Without aids
- Marking scale
- 7-point grading scale
- Censorship form
- External censorship
- Exam period
End of January (after Blok 2)
Criteria for exam assesment
The requirement for passing the exam is >50% correct asignment (based on an overall assessment).
The student should be able to use the appropriate terminology to describe the normal histology of most tissues and organs, be able to recognize and describe relevant pathologic morphologic alterations at the microscopic level, and reflect about important functional consequence.
Moreover, the student should be able to convey and reflect about the current pathophysiologic theories and molecular mechanisms related to the development of the included diseases.