SBRI19015U Clinical Translational Medicine

Volume 2024/2025
Education

BRIDGE - Translational Excellence Programme

Content

Understanding mechanisms behind and developing new treatment for major public health challenges such as infectious-, heart-, liver-, and lung diseases, diabetes, rheumatoid arthritis, and cancer involve the movement of the research from bench to clinic and from clinic to bench. It can be a challenging process, and the BRIDGE Clinical Translational Medicine course covers examples on how to bridge the gap between basic and clinical research by an introduction to general topics and challenges in clinical translational research as well as relevant real-life examples.

Learning Outcome

Upon completing the course, participants should be able to:

 

Knowledge

  • Relate how thorough characterization (molecular, immunological, imaging) of the individual patient or patient’s samples may be used for direct selection of patient treatment/care.
  • Explain how information from biological experiments (in vitro and animal models) can be used as a platform for designing investigations in patients.
  • Discuss how biological experiments may lead to drug development.
  • Describe how to bring a preclinical drug to phase 1, basic requirements.
  • Plan a translational study with material from a clinical trial.

 

Skills

  • Integrate knowledge obtained from other courses into translational clinical research.
  • Critically evaluate preclinical data - from a clinical point of view.
  • Generate novel ideas for clinical trials from preclinical observations.
  • Implement research results in clinical practice.
  • Solve unmet clinical needs/questions by designing the clinically relevant preclinical/ biological experiments.
     

Competences

  • Integrate basic biology into clinical knowledge.
  • Assess ethical considerations of how to implement new molecular tools and conduct studies with patients.
  • Understand the central aspects of clinical translational medicine and be able to discuss and communicate these to other scientists, clinicians, and the public.
Literature

Course literature will be published on Absalon.

Participants must meet the admission criteria of the BRIDGE - Translational Excellence Programme.
Cathedral lectures and discussion sessions.

The course will end with an evaluation where participants must reflect on course learning outcomes and give feedback for course development.
  • Category
  • Hours
  • Lectures
  • 22
  • Class Instruction
  • 1
  • Preparation
  • 4
  • Exercises
  • 1
  • Project work
  • 2
  • Total
  • 30
Oral
Continuous feedback during the course of the semester
Credit
0 ECTS
Type of assessment
Continuous assessment
Requirement to attend classes
Type of assessment details
Attendance and active participation.
Exam registration requirements

Participants are automatically registered for the examination upon admission to the BRIDGE - Translational Excellence Programme.

Aid
All aids allowed
Marking scale
passed/not passed
Censorship form
No external censorship
Criteria for exam assesment

Active contribution and course participation according to the BRIDGE Guidelines and Practicalities.