NMAK14029U Statistics for Bioinformatics and eScience (StatBI/E)
MSc Programme in Bioinformatics
The course will take the participants through the following content.
- Standard discrete and continuous distributions, descriptive methods, Bayes’ theorem, conditioning, independence, and selected probability results.
- Mean, variance, estimators, two-sample comparisons.
- Maximum likelihood and least squares estimation.
- Standard errors and confidence intervals.
- Correlation, (generalized) linear and non-linear regression.
- The statistical programming language R and R notebooks.
The basic concepts in mathematical statistics, such as;
- Probability distributions
- Standard errors and confidence intervals
- Maximum likelihood and least squares estimation
- Hypothesis testing and p-values
- (Generalized) Linear and non-linear regression
- Master basic implementation in R and generation of analysis reports using R notebooks.
- Use computer simulations for computations with probability distributions, including bootstrapping.
- Compute uncertainty measures, such as standard errors and confidence intervals, for estimated parameters.
- Compute predictions based on regression models taking into account the uncertainty of the predictions.
- Assess a fitted distribution using descriptive methods.
- Use general purpose methods, such as the method of least squares and maximum likelihood, to fit probability distributions to empirical data.
- Summarize empirical data and compute relevant descriptive statistics for discrete and continuous probability distributions.
- Formulate scientific questions in statistical terms.
- Interpret and report the conclusions of a practical data analysis.
- Assess the fit of a regression model based on diagnostic quantities and plots.
- Investigate scientific questions that are formulated in terms of comparisons of distributions or parameters by statistical methods.
- Investigate scientific questions regarding association in terms of (generalized) linear and non-linear regression models.
Academic qualifications equivalent to a BSc degree is recommended.
- Practical exercises
- 7,5 ECTS
- Type of assessment
- Continuous assessmentThe exam consists of two parts: (1) two quiz assignments (60%), and (2) a 30-hours written take-home assignment (40%) in course week 8.
The first part consist of online assignments in form of quizzes; students need to upload their written derivations for their solutions to the quiz questions and submit their final answers via the quiz form; students need to submit their solutions within a week after each quiz is being made available on the course webpage.
All parts need to be completed individually.
Each part-exam is assessed and weighted individually, and the final grade is determined based on this. Students can pass the exam without passing all part-exams if the total grade is 02 or higher.
- All aids allowed
- Marking scale
- 7-point grading scale
- Censorship form
- No external censorship
One internal examiner
The re-exam of part (1) takes the form of a 20 minutes oral exam without preparation. The re-exam of part (2) takes the same form as the ordinary part-exam.
Successfully passed part-exams do not have to be repeated; yet, students can choose to participate in the various part-re-exams in which case they need to inform the course responsible (at least 4 weeks before the re-exam) if they wish to repeat it. Results of part-exams that are not repeated will be included in the assessment of the re-exam with the result obtained when they were taken the first time.
If ten or fewer students have signed up for the re-exam, the type of assessment may be changed to a 30 minutes oral exam with 30 minutes preparation. All aids allowed.
Criteria for exam assesment
In order to obtain the grade 12 the student should convincingly and accurately demonstrate the knowledge, skills and competences described under Learning Outcome.
- Course code
- 7,5 ECTS
- Full Degree Master
- 1 block
- Block 2
- Course capacity
- No limit.
- Course is also available as continuing and professional education
- Study board
- Study Board for the Biological Area
- Department of Mathematical Sciences
- Faculty of Science
- Sebastian Weichwald (10-7a7e6c706a6f7e68736b4774687b6f35727c356b72)