SMTK20002E Exam in Advanced Physiological Modelling

Volume 2021/2022

MSc Programme of Biomedical Engineering - Restricted elective in the Technological Specialization

MSc Quantitative Biology and Disease Modelling - Restricted elective in the Technological Specialization

  • Category
  • Hours
  • Project work
  • 24
  • Exam
  • 1
  • Total
  • 25
7,5 ECTS
Type of assessment
Written assignment, -
Oral examination, 30 min.
Oral exam includes a presentation of the project on the basis of the written report and discussion of biological, mathematical, and computational aspects of the project.
Exam registration requirements

Achieved course attestation (SMTK20001E) by handing-in of project assignment and assessment/criticism of received assignment.

Without aids
Marking scale
7-point grading scale
Censorship form
No external censorship
One internal examiner
Criteria for exam assesment

In order to obtain the grade 12, the student must demonstrate the following abilities at a sufficient level:


  • Explain physiology and regulatory mechanisms related to normal and pathological conditions
  • Understand mathematical/physics concepts underlying modeling approach
  • Understand computational algorithms behind scripts related to biosimulations
  • Understand assumptions and simplifications needed to build a reliable model
  • Understand dynamical/statistical features of the model and their relevance to certain pathological conditions



  • Review of scientific literature on physiological modeling and related data analysis, critically assess the use of methods and obtained results
  • Discuss reproducibility and comparability of relevant computational models and approaches
  • Perform theoretical and computational analysis of dynamical patterns of physiological models and reveal parameters responsible for pathological conditions
  • Optimize/develop computation algorithms to perform biosimulations
  • Convey results into a scientifically written report and a Power Point presentation