SBRI19015U  Clinical Translational Medicine

Volume 2019/2020
Education

BRIDGE - Translational Excellence Programme

 

Content
  • Translational research study design
  • How to develop and interpret PDX models
  • Automatized drug-screening in real time - for patient care
  • Clinical trial design
  • Communication training between patients, clinicians, basic scientist and industry
  • Phase 1 studies
  • First in human studies
  • Discussion clinical cases including ethical issues
  • Career moves from academia to industry
Learning Outcome

On completion of the course, the participants should be able to:

Knowledge

  • Relate how thorough characterization (molecular, immunological, imaging) of the individual patient or patient’s samples may be used for direct selection of patient treatment/care
  • Explain how information from biological experiments (in vitro and animal models) can be used as a platform for designing investigations in patients
  • Discuss how biological experiments may lead to drug development
  • Describe how to bring a preclinical drug to phase 1, basic requirements
  • Describe Phase 1 -> 3 trials
  • Plan a translational study with material from a clinical trial
  • Describe different studies, non-inferior vs. superiority studies

 

Skills

  • Integrate knowledge obtained from all other courses into translational clinical research
  • Critically evaluate preclinical data -  from a clinical point of view
  • Generate novel ideas for clinical trials from preclinical observations
  • Implement research results in clinical practice
  • Solve unmet clinical needs/questions by designing the clinically relevant preclinical/ biological experiments

 

Competences

  • Integrate  basic biology  into clinical knowledge
  • Assess ethical considerations of how to implement new molecular tools and conduct studies with patients
  • Understand the central aspects of clinical translational medicine and be able to discuss and communicate these to other scientists, clinicians, and the public

To be added

Participants must meet the admission criteria in BRIDGE - Translational Excellence Programme
Individual projects – presentations
Cathedral lectures
Industry visit
Patient involvement – a story from a patient
Phase 1 visit
Oral
Continuous feedback during the course of the semester
Credit
0 ECTS
Type of assessment
Continuous assessment
Course participation
Attendance and active participation
Exam registration requirements

Participants are automatically registered for the Examination upon course registration.

Aid
All aids allowed
Marking scale
passed/not passed
Censorship form
No external censorship
  • Category
  • Hours
  • Lectures
  • 22
  • Excursions
  • 4
  • Project work
  • 5
  • Course Preparation
  • 5
  • Practical Training
  • 6
  • Total
  • 42