SBRI19002U Translational Discovery Omics II
BRIDGE - Translational Excellence Programme
A two-year postdoctoral fellowship in translational medicine
The aim of the course is to provide the participants with: i) an overview of the major high-end quantitative proteomics technologies with focus on mass spectrometry; ii) an overview of the wealth of biological applications that quantitative proteomics screens can be applied in, including proteome quantitation post translational modification (PTM) analysis and protein-protein interactions; and iii) introduction on how to process proteomics data at different levels.
The main themes covered in the course include:
- Mass spectrometry technologies and principles for protein sequencing.
- Introduction to proteomics
- Applications of quantitative proteomics in biology. The use of proteomics in industry and academia.
Upon completing the course, participants should be able to:
- Demonstrate a basic understanding of different mass spectrometry-based proteomics workflows and methods.
- Gain a general understanding of the main statistical concepts required for proteomics analysis.
- Comprehend different models of proteomics analysis in different research settings.
- Grasp the role of protein signaling pathways and protein-protein interactions in health and disease.
Skills and Competences
- Be able to perform mass spectrometry of biological based proteomics analysis of biological samples.
- Process raw mass spectrometry data and obtain peptide and protein identification from proteomics analysis using different software tools.
- Use data analysis and visualization programs such as MaxQuant, Spectronaut, Perseus, R, and Cytoscape and integrate proteomics data with curated datasets such as signaling pathways and protein-protein interactions.
- Understand the central aspects of translational omics and be able to discuss and communicate these to other scientists, clinicians, and the public
- Critically evaluate the results and interpretation of downstream data analysis to answer biological questions and hypotheses.
Course literature is published on Absalon.
- Class Instruction
- Theory exercises
Automatic registration upon appointment in the Translational Excellence Programme
- 0 ECTS
- Type of assessment
- Continuous assessmentCourse participationAttendance and active participation
- Exam registration requirements
Participants are automatically registered for the Examination upon course registration.
- All aids allowed
- Marking scale
- passed/not passed
- Censorship form
- No external censorship
Criteria for exam assesment
Active contribution and course participation according to the BRIDGE Guidelines.
- Course code
- 0 ECTS
- Part Time Master
- See course dates and course programme in Absalon
- Course capacity
- 15 participants
- Course is also available as continuing and professional education
- Study board
- Study Board for the Professionel Master´s Degree Programmes at The Faculty og Health and Medical Science
- Center for Protein Research
- Faculty of Health and Medical Sciences
- Jesper Velgaard Olsen (12-6d687673687531726f76687143667375316e7831676e)
- Marie Sofie Yoo Tollenaere-Larsen (12-7064756c68316f647576687143667375316e7831676e)