SBRI19001U Translational Discovery Omics I - Genomics, Transcriptomics, and Metabolomics
BRIDGE - Translational Excellence Programme
The aim of the course is to provide the participants with:
i) an overview of theory and application of technologies in genetic
research in health and disease,
ii) an introduction to the impact of genetics in precision medicine, and
iii) an understanding of application of technologies in transcriptomics and single-cell sequencing research.
The main themes covered in the course include:
- Phenotype definition
- Genetic variation in health and disease
- Genetic variation in personalized medicine
- Methods in genome research including genome sequencing
- Analytical methods in genome research
- Transcriptomics
- RNA sequencing incl. single cell sequencing
This course mostly focus on basic omics. The translation of omics is included in later omics courses in the BRIDGE Programme.
Upon completing the course, participants should be able to:
Knowledge
- Demonstrate an understanding of the impact of genetic variation in health and disease.
- Discuss the potential applications of modern techniques to study genomic variation.
- Have an awareness of strengths and limitations of translation of genetic variation into translational medicine.
- Get an understanding of the potential different applications of nucleotide and RNA sequencing.
- Show a comprehension of the principles and application of transcriptomic profiling of tissues and single cells.
Skills
- Critically evaluate results from studies of genetic variation in humans.
- Apply simple tools to infer relationships between individuals and populations using genetic data.
- Design an appropriate study of the genetics of a human diseases.
Competences
- Understand the central aspects of translational omics and be able to discuss and communicate to other scientists, clinicians, and the public.
Course literature will be published on Absalon.
The course will end with an evaluation where participants must reflect on course learning outcomes and give feedback for course development.
- Category
- Hours
- Lectures
- 12,5
- Class Instruction
- 5
- Preparation
- 3
- Theory exercises
- 3,5
- Total
- 24,0
The BRIDGE – Translational Excellence Programme offers a few selected graduated PhDs a two-year postdoctoral fellowship in translational medicine. The courses are only available to the fellows enrolled in the programme. Fellows are automatically enrolled in the courses upon admission to the programme.
For further information about the programme, please go to the BRIDGE website: www.bridge.ku.dk
- Credit
- 0 ECTS
- Type of assessment
- Continuous assessmentCourse participation
- Type of assessment details
- Attendance and active participation.
- Exam registration requirements
Participants are automatically registered for the examination upon admission to the BRIDGE - Translational Excellence Programme.
- Aid
- All aids allowed
- Marking scale
- passed/not passed
- Censorship form
- No external censorship
Criteria for exam assesment
Active contribution and course participation according to the BRIDGE Guidelines and Practicalities.
Course information
- Language
- English
- Course code
- SBRI19001U
- Credit
- 0 ECTS
- Level
- Part Time MasterPh.D.
- Placement
- Autumn
- Schedule
- See course dates and course programme in Absalon.
- Course capacity
- 15 participants
Study board
- Study Board for the Professionel Master´s Degree Programmes at The Faculty og Health and Medical Science
Contracting department
- The Novo Nordisk Foundation Center for Basic Metabolic Research
Contracting faculty
- Faculty of Health and Medical Sciences
Course Coordinators
- Torben Hansen (torben.hansen@sund.ku.dk)
- Niels Grarup (niels.grarup@sund.ku.dk)
- Mette Andersen Lepola (Metteandersen@sund.ku.dk)