SBRI19001U Translational Discovery Omics I

Volume 2020/2021

BRIDGE - Translational Excellence Program



The main themes covered in the course include:

  • Phenotype definition
  • Genetic variation in health and disease
  • Genetic variation in personalized medicine
  • Pharmacogenetics
  • Methods in genome research including genome sequencing
  • Analytical methods in genome research
  • transcriptomics
  • RNA sequencing incl. single cell sequencing
Learning Outcome

Upon completing the course, participants should be able to:


  • Demonstrate an understanding of the impact of genome variation on health and disease
  • Discuss the potential applications of modern techniques to study genomic variation
  • Have an awareness of strengths and limitations of translation of genome variation into translational medicine
  • Have an understanding of the potentials different applications of nucleotide and RNA sequencing
  • Show comprehension of the principles and application of transcriptomic profiling of tissues and single cells



  • Critically evaluate results from studies of genetic variation in humans
  • Apply simple tools to infer relationships between individuals and populations using genetic data
  • Design an appropriate genomic study of human diseases



  • Understand the central aspects of translational omics and be able to discuss and communicate to other scientists, clinicians, and the public.
Participants must meet the admission criteria in BRIDGE - Translational Excellence Programme
The course is organized with a mixture of scientific seminars by invited speakers, including technical lectures about modern technologies, and student-led activities. In addition, the course will include group work, case studies, and practical exercises.
  • Category
  • Hours
  • Lectures
  • 15
  • Class Instruction
  • 5
  • Preparation
  • 5
  • Theory exercises
  • 5
  • Total
  • 30
Continuous feedback during the course of the semester
Type of assessment
Continuous assessment
Course participation
Attendance and active participation
Exam registration requirements

Participants are automatically registered for the Examination upon course registration.

All aids allowed
Marking scale
passed/not passed
Censorship form
No external censorship
Criteria for exam assesment

i) an overall overview of the potentials of omics-driven translational research,

ii) an overview (theory and application) of technologies in genetic research of health and disease, and

iii) an overview (methods and application) or RNA profiling in relation to health and disease.