NPLK14006U Pesticide Use, Mode of Action and Ecotoxicology
MSc Programme in Agriculture
MSc Programme in Environmental Science
The rationale behind the development of pesticides, their use and their regulation is the frame of references of the course. The importance of mode of action and site(s) of action of pesticides will be stressed and linked to chemical properties, uptake, translocation and metabolism in target and non-target organisms. The principles of assessing pesticide selectivity will be an integral part of the course. We deal with formulations of pesticides and use of adjuvants to enhance efficacy, either by the manufacture or by the end user. Various reference models to assess joint action of pesticide mixtures are taught and the implication to their use is validated and side effects are described. We focus on aquatic and terrestrial ecotoxicology in relation to pesticide loads, intentional and not intentional discharge in the environment and also the ecotoxicological effects of pesticides on populations and communities. Risk assessment of the pesticide use is evaluated in relation to ecotoxicology, and the national and international registration systems. An excursion to FMC-European Innovation Center, the section of Research and Development of the only Danish pesticide producing company (http://www.fmc.com/careers/denmark) and a visit on a demo-farm is an integral part of the course.
The students should know about the scientific principles of how chemical, physical and biological properties of pesticides affect uptake, distribution, metabolisation and excretion of the pesticides, and how the mode of action of the pesticide determines their effect on different organisms. They should know about pesticide use in agriculture, horticulture, forestry, public land and households and about their ecotoxicological side effects. And they should know how knowledge on adverse effects on humans and the environment is used in the risk assessment and legislation of pesticides in Europe. The curriculum encompasses the advantages and disadvantages of pesticide use, the knowledge of which is instrumental for those who wish to work with pesticide development, their management and use in industry, agriculture, horticulture, forestry and on public domains, their legislation and registration.
- - Know how chemical and physical properties of pesticides affect uptake, distribution, metabolisation and excretion of pesticides in plants and animals
- - Know the site and mode of action of exemplary pesticides representing the most used pesticide groups
- - Know the principles of pesticide use in crops and for non-agricultural purposes (pest and vector control) including their effects on both target and non-target organisms
- - Know how pesticide effects on humans and the environment is assessed
- - Know the rationale behind pesticide development and registration
- -Set up experiments to test for the effect of herbicides, fungicides and insecticides on target or non-target organisms
- - Statistical analysis and biological interpretation of dose-response data from bioassays with various organisms and endpoints (binary and gradual endpoints)
- - Analyse and interpret data from mixtures toxicity experiments
- - Assess efficacy/toxicity of herbicides and recognise characteristic symptoms of exemplary modes of action
- - Evaluate toxicity data in a regulatory context
- - Apply quantitative methods to assess pesticide load, drift and fate in organisms and environment
- - Evaluate pesticide applications to target and non-target organisms in the terrestrial and aquatic environments
- - Put various theories and principles of pesticide action into perspective and make sound judgment of impact of pesticides on different environments
- - Discuss pesticide use from a scientific stand in view of its controversial issue in the public
The exact editions will be written on Absalon.
Examples of course literature:
Stephenson G.R. and Solomon K.R, Pesticides and the Environment,
CNTC Canadian Network of Toxicology Centres.
Cedergreen, N. 2017, Manual for laboratory and theoretical exercices
Written and oral feedback is given for all reports on a report-group basis. All reports thereafter have to be re-submitted. Peer-feedback is given on the final presentation, with different groups being asigned to give feedback on the individual presentations. All students are encurraged to ask questions to practical and theoretical exersises during the course and can be expected to recieve feedback on their questions and enquiries.
- 7,5 ECTS
- Type of assessment
- Oral examination, 20 minOral examination in reports and curriculum, 20 min. preparation
- Exam registration requirements
All exercise reports are submitted and approved
- All aids allowed
- Marking scale
- 7-point grading scale
- Censorship form
- No external censorship
One internal censor
If the requirement is not met, the student has to follow the course the following year as the laboratory exercises need to be followed.
Criteria for exam assesment
See description of learning outcome
- Theory exercises
- Practical exercises
- Project work