NBIK13005U CHANGED: Experimental Higher Model Organisms
MSc Programme in Biology
MSc Programme in Biochemistry
MSc Programme in Biology with a minor subject
Theoretical exercises, colloquia and lectures will give a
critical review of the use of genetic model systems and strategies
used in basic and applied research. Laboratory exercises will
include a range of techniques such as:
1) Vector construction and genome, transcriptome and/or proteome database mining
2) Genomic manipulations via homologous recombination, random insertion, RNAi, morpholinos, etc.
3) Stable transformation and transient transfection,
4) Transgenic analyses with marker enzymes and/or tagged proteins.
The techniques will be applied to cells and organisms such as vertebrates, zebrafish D. rerio, worm C. elegans, fruit fly D. melanogaster, moss P. patens and/or flowering plant A. thaliana.
By the end of the course, students are expected to have the
following knowledge, skills and competences:
Knowledge of the research fields with model organisms included in the curriculum covered by assigned reading, lectures, seminar presentations and written reports.
- Explain developments in the fields presented by the teachers
- Describe in detail the methodologies used in these fields
- Explain and exemplify the technologies used in these fields
- Present assigned original research papers
- Submit assigned written papers
- Be able to give a detailed description of and evaluate the exercises presented during the course.
- Discuss and criticize research articles orally and in writing
- Interpret different types of experimental data introduced in the course
- Discuss interdisciplinary aspects of the research covered in the course
- Propose experiments to test models and questions raised in research on model organisms.
- 7,5 ECTS
- Type of assessment
- Written examination, 3 hours under invigilationCHANGED: The written exam is arranged by the department.
- Exam registration requirements
CHANGED: Active participation in 80 % of exercises, 1-2 oral presentations of published original research papers, 6-8 written reports.
- All aids allowed
- Marking scale
- 7-point grading scale
- Censorship form
- No external censorship
Several internal examiners.
CHANGED: As ordinary.
Students who do not fulfill the requirements for attending the ordinary exam will have to follow the course again.
Criteria for exam assesment
See Learning outcome.
- Theory exercises
- Project work