NBIB15021U Fundamental Bioinformatics

Volume 2023/2024

BSc Programme in Biochemistry
BSc Programme in Biology


Biological databases, sequence alignment (pairwise and multiple), phylogeny, genomics, next generation sequencing, expression analysis, RNA-seq, RNA structure, systems biology.

Learning Outcome

After successfully completing the course students will be able to use, apply and understand the most important bioinformatical tools and theories that can facilitate their future work in biological sciences (e.g. biology, biochemistry, biomedicine etc.).


At the conclusion of the course, the students should be able to:

  • Explain the basic concepts behind the covered topics.
  • Describe the major algorithms covered.
  • Suggest computational tools that could be used to solve a given biological problem.


At the conclusion of the course, the students should be able to:

  • Apply programs for performing sequence alignment (pairwise and multiple), constructing phylogenies, predict RNA structure and analyse expression data.
  • Find and use Biological databases for retrieving and displaying information.
  • Work with data from next generation sequencing experiments.


At the conclusion of the course, the students should be able to:

  • Perform a correct computational analysis of a given biological problem, which includes the selection of relevant tools.
  • Explain and discuss strengths and weaknesses of the applied tools and how these affect the obtained results.
  • Suggest further analyses that could improve the results obtained.

See Absalon.

Basic genetics, biochemistry (incl. protein chemistry) and molecular biology.

The course is mandatory for Biochemistry. Biology students are generally not recommended to take this course in their second year. It is recommended that biology students have passed Matematik/Statistik, Almen Biokemi, Almen Molekylærbiologi and Evolutionsbiologi before taking this course. Molecular Biomedicine students are recommended to have passed Biokemi and Molekylærbiologi.
Flipped classroom teaching. The students watch recorded lectures and answer simple multiple choice quizzes before the class. During class exercises are solved in small group. In the workshops, more elaborate exercises are solved with help from assistant teachers.
6 weeks with max 9 hours per week (6 hours class/problemsolving + 3 hours workshop exercises), followed by 1 week to solve an exam assignment.
Students should bring a laptop computer to fully benefit from the course, since the use of computers is an integrated part of the course. Students should know how to use and administer their computer. No expert knowledge or programming skills are needed. See course homepage for more details.
  • Category
  • Hours
  • Lectures
  • 42
  • Preparation
  • 142,5
  • Theory exercises
  • 21
  • Exam
  • 0,5
  • Total
  • 206,0
Continuous feedback during the course of the semester
Feedback by final exam (In addition to the grade)
7,5 ECTS
Type of assessment
Oral examination, 25 minutes (no preparation)
Type of assessment details
Individual exam based on a one week practical assignment.
Without aids
Marking scale
7-point grading scale
Censorship form
No external censorship
Several internal examiners.
At the oral exam an examiner and an internal censor will be present.

Oral exam (25 min.) based on curriculum and the exam assignment (no preparation and no aids).

Criteria for exam assesment

In order to obtain the grade 12 the student should convincingly and accurately demonstrate the knowledge, skills and competences described under Learning Outcome.