SKBK18002U Molecular Pathology

Volume 2019/2020
Education

KA i kvantitativ biologi og sygdomsmodellering - obligatorisk

Msc in Quantitative Biology and Disease Modelling - compulsory

The course is co-taught with the identical course SMOK15001U in Molecular Pathology at the MSc programme in Molecular Biomedicine.

Content

The focus of the course is the study of disease, including the cause (etiology), mechanisms of development (pathogenesis), and structural/functional alterations involved. The course covers the pathologic basis of a broad range of common diseases, including the normal histology of relevant tissues and organs required to identify pathological lesions. Main topics include cell injury, adaptation, and death; inflammation; neoplasia; and cardiovascular, immunological, infectious, neurological, metabolic, and musculoskeletal diseases. There is a focus on definitions, terminology, and the description of morphological changes in cells and tissues, as illustrated by clinical examples. There is a strong emphasis on current pathophysiological theories and molecular disease mechanisms, which will be covered by lectures and critically discussed during student activating lessons. 

Learning Outcome

Knowledge

The student will acquire a broad understanding of pathologic concepts and a profound knowledge of the most common diseases and their underlying mechanisms.

Skills

The successful student will know the normal histology of most tissues and organs, be able to recognize and describe relevant pathologic morphologic alterations at the microscopic level, and understand important functional consequence. The student will be familiar with the pathologic terminology, and should know and be able to describe the current pathophysiologic theories and molecular mechanisms related to the development of the included diseases.

Competences

The course should provide the student the theoretical foundation required to engage in critical reading and discussion of disease mechanisms and the capacity to relate basic knowledge to more clinical aspects of the relevant diseases. 

Literature

Recommended textbooks are Robbins & Cotran: Pathologic Basis of Disease, 9th Ed. and Ross & Pawlina: Histology – A Text and Atlas 7th Ed. (or any similar histology book).

Case material and original articles discussed at journal clubs.

Suggested readings will be available on Absalon.

It is required that the student has a strong knowledge of cell biology. Knowledge of human physiology is an advantage.
Lectures: 28 h
Microscopy lessons in normal histology: 12 h
Microscopy lessons in pathology: 14 h
CASE lessons: 14 h
Journal clubs: 14 h
Lessons for exam preparation: 2 h
Preparation: 328 h
Total: 412
All course materials, correspondence, and examination are in English
  • Category
  • Hours
  • Class Instruction
  • 26
  • Exam
  • 4
  • Exam Preparation
  • 2
  • Exercises
  • 28
  • Lectures
  • 28
  • Preparation
  • 324
  • Total
  • 412
Peer feedback (Students give each other feedback)

There will be feedback from lecturers as well as peer-feedback on "student presentations/journal clubs.

Credit
15 ECTS
Type of assessment
Written examination, 4 hours under invigilation
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Aid
Without aids
Marking scale
7-point grading scale
Censorship form
External censorship
Exam period

End of January (after Blok 2)

Criteria for exam assesment

The requirement for passing the exam is >50% correct asignment (based on an overall assessment).

The student should be able to use the appropriate terminology to describe the normal histology of most tissues and organs, be able to recognize and describe relevant pathologic morphologic alterations at the microscopic level, and reflect about important functional consequence.

Moreover, the student should be able to convey and reflect about the current pathophysiologic theories and molecular mechanisms related to the development of the included diseases.