NBIK13005U Experimental Higher Model Organisms

Volume 2019/2020
Education

MSc Programme in Biology
MSc Programme in Biochemistry
MSc Programme in Biology with a minor subject

Content

Theoretical exercises, colloquia and lectures will give a critical review of the use of genetic model systems and strategies used in basic and applied research. Laboratory exercises will include a range of techniques such as:

1) Vector construction and genome, transcriptome and/or proteome database mining
2) Genomic manipulations via homologous recombination, random insertion, RNAi, morpholinos, etc.
3) Stable transformation and transient transfection,
4) Transgenic analyses with marker enzymes and/or tagged proteins.

The techniques will be applied to cells and organisms such as vertebrates, zebrafish D. rerio, worm C. elegans, fruit fly D. melanogaster, moss P. patens and/or flowering plant A. thaliana.

Learning Outcome

By the end of the course, students are expected to have the following knowledge, skills and competences:

Knowledge of the research fields with model organisms included in the curriculum covered by assigned reading, lectures, seminar presentations and written reports.

Skills to:

  • Explain developments in the fields presented by the teachers
  • Describe in detail the methodologies used in these fields
  • Explain and exemplify the technologies used in these fields
  • Present assigned original research papers
  • Submit assigned written papers
  • Be able to give a detailed description of and evaluate the exercises presented during the course.


Competences to:

  • Discuss and criticize research articles orally and in writing
  • Interpret different types of experimental data introduced in the course
  • Discuss interdisciplinary aspects of the research covered in the course
  • Propose experiments to test models and questions raised in research on model organisms.
Literature

See Absalon.

General Molecular Biology/Almen molekylærbiologi or an equivalent course.

Academic qualifications equivalent to a BSc degree is recommended.
Introduction lessons in theoretical backgrounds and practical classes including summaries and discussions of reports.
  • Category
  • Hours
  • Colloquia
  • 21
  • Lectures
  • 28
  • Preparation
  • 85
  • Project work
  • 51
  • Theory exercises
  • 21
  • Total
  • 206
Written
Oral
Individual
Collective
Continuous feedback during the course of the semester
Credit
7,5 ECTS
Type of assessment
Written examination, 3 hours under invigilation
The written exam is arranged by the department.
Exam registration requirements

Active participation in 80 % of exercises, 1-2 oral presentations of published original research papers, 6-8 written reports.

Aid
All aids allowed
Marking scale
7-point grading scale
Censorship form
No external censorship
Several internal examiners.
Re-exam

The same as the ordinary exam.

Students who do not fulfill the requirements for attending the ordinary exam will have to follow the course again.

 

Criteria for exam assesment

See Learning outcome.