NBIK13005U CHANGED: Experimental Higher Model Organisms

Volume 2018/2019
Education

MSc Programme in Biology
MSc Programme in Biochemistry
MSc Programme in Biology with a minor subject

Content

Theoretical exercises, colloquia and lectures will give a critical review of the use of genetic model systems and strategies used in basic and applied research. Laboratory exercises will include a range of techniques such as:

1) Vector construction and genome, transcriptome and/or proteome database mining
2) Genomic manipulations via homologous recombination, random insertion, RNAi, morpholinos, etc.
3) Stable transformation and transient transfection,
4) Transgenic analyses with marker enzymes and/or tagged proteins.

The techniques will be applied to cells and organisms such as vertebrates, zebrafish D. rerio, worm C. elegans, fruit fly D. melanogaster, moss P. patens and/or flowering plant A. thaliana.

Learning Outcome

By the end of the course, students are expected to have the following knowledge, skills and competences:

Knowledge of the research fields with model organisms included in the curriculum covered by assigned reading, lectures, seminar presentations and written reports.

Skills to:

  • Explain developments in the fields presented by the teachers
  • Describe in detail the methodologies used in these fields
  • Explain and exemplify the technologies used in these fields
  • Present assigned original research papers
  • Submit assigned written papers
  • Be able to give a detailed description of and evaluate the exercises presented during the course.


Competences to:

  • Discuss and criticize research articles orally and in writing
  • Interpret different types of experimental data introduced in the course
  • Discuss interdisciplinary aspects of the research covered in the course
  • Propose experiments to test models and questions raised in research on model organisms.
Literature

See Absalon.

General Molecular Biology/Almen molekylærbiologi or an equivalent course.
Introduction lessons in theoretical backgrounds and practical classes including summaries and discussions of reports.
  • Category
  • Hours
  • Colloquia
  • 21
  • Lectures
  • 28
  • Preparation
  • 85
  • Project work
  • 51
  • Theory exercises
  • 21
  • Total
  • 206
Written
Oral
Individual
Collective
Continuous feedback during the course of the semester
Credit
7,5 ECTS
Type of assessment
Written examination, 3 hours under invigilation
CHANGED: The written exam is arranged by the department.
Exam registration requirements

CHANGED: Active participation in 80 % of exercises, 1-2 oral presentations of published original research papers, 6-8 written reports.

Aid
All aids allowed
Marking scale
7-point grading scale
Censorship form
No external censorship
Several internal examiners.
Re-exam

CHANGED: As ordinary.

Students who do not fulfill the requirements for attending the ordinary exam will have to follow the course again.

 

Criteria for exam assesment

See Learning outcome.