NKEA08006U Heterocyclic Chemistry
MSc Programme in Chemistry
MSc Programme in Medicinal Chemistry
Synthesis and reactivity of simple heteroaromatic compounds: pyridines, quinolines, diazines, pyrylium salts, pyrones, furans, thiophenes, indoles and different five-membered rings with two heteroatoms. Nomenclature in heterocyclic chemistry. Some applications of heterocyclic compounds.
The student should be able to suggest syntheses of simple heterocyclic compounds and explain the reactivity of heteroaromatic compounds.
The student should be able to identify differences in reactivities of heterocyclic compounds and be able to demonstrate how heterocyclic compounds can be prepared from simple starting materials. Moreover, the student should be able to name both mono- and polycyclic heterocyclic compounds.
Synthesis and reactivity of heterocyclic compounds. Particular focus on pyridines, quinolines, diazines, pyrylium salts, pyrones, furans, thiophenes, pyrrols, indoles, benzothiophenes, and benzofurans.
J. A. Joule, K. Mills, ”Heterocyclic Chemistry”, 5th Ed.,
M. B. Nielsen, Notes: Naming Heterocyclic Compounds
- 7,5 ECTS
- Type of assessment
- Oral examination, 30 min.Oral examination (about 30 min.) in one of the topics of the course. The student will pick a question based on one of the heterocyclic compound classes that has been covered, or a question based on more general concept. Examples of possible questions: "Explain the reactivity and synthesis of thiophenes", "Compare the reactivity of nitrogen-containing heterocycles", "Give an overview of ring-opening reactions in heterocyclic chemistry," or "Give an overview of heterocycle synthesis by cycloaddition". The student should present the topic at the blackboard without any aids. The examiner will also ask questions outside the specific question that was arbitrarily picked by the student. The student will also be asked to name one specific compound.
- Marking scale
- passed/not passed
- Censorship form
- External censorship
As ordinary exam
Criteria for exam assesment
The student should satisfy the learning outcomes.
- Theory exercises