SMOB14001U Cellular Neuroscience
The goal of the course is to give the students an overview of
methods used to study functions of the central nervous system. We
provide an insight in signaling mechanisms in neurons and networks
of neurons by describing how the molecular mechanisms of electrical
and chemical signalling are adapted to serve synaptic transmission,
synaptic integration and nerve impulse generation. The Course
illustrates how experiments led to textbook knowledge and provide
insight in experimental procedures, techniques and preparations.
The course includes theoretical and practical elements. The theory
focuses on cellular and molecular properties of neurons and their
implications in physiological functions.
In addition to basic subjects, the course highlights a) The role of
the non-linear postsynaptic properties provided by voltage
sensitive ion channels in dendrites.
b) Modulation of these properties by G-protein coupled receptors.
c) Functional specialization of cell types in particular brain
regions and
d) Signaling networks in particular brain regions.
The Practical part includes demonstrations of preparations of nerve
tissues in vitro, recording electrical activity from neurons with
patch clamp techniques in slices preparations. Each student gets
the opportunity to record from living neurons and to characterize
some of the transmembrane currents responsible for firing
properties by means of electrophysiological and pharmacological
tools.
Cellular and Molecular Neurophysiology, 4th Edition
- Category
- Hours
- Class Instruction
- 15
- Exam
- 0,5
- Lectures
- 15
- Practical exercises
- 12
- Preparation
- 163,5
- Total
- 206,0
- Credit
- 7,5 ECTS
- Type of assessment
- Oral examinationAn oral presentation of one article on a self chosen subject within the course combined with a discussion, with participation of an internal or external examiner.
- Exam registration requirements
- The practical laboratory course must be approved to participate in the examination.
- Aid
- All aids allowed
- Marking scale
- 7-point grading scale
- Censorship form
- No external censorship
More than one internal examiner
- Exam period
- Week 45, 2014
Criteria for exam assesment
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Course information
- Language
- English
- Course code
- SMOB14001U
- Credit
- 7,5 ECTS
- Level
- Bachelor
- Duration
- 1 block
- Placement
- Block 1 And Block 4
- Schedule
- C (Mon 13-17 + Wednes 8-17)
- Course capacity
- 32 participants
- Study board
- Study Board of Biomolecular Sciences and Technology
Contracting department
- Department of Neuroscience and Pharmacology
Course responsibles
- Jean-Francois Marie Perrier (7-726774746b67744275777066306d7730666d)