SLVKB0351U Principles of Pharmacology
- Neurotransmitter systems and neuropharmacology
- Fundamental nerve/muscle/cell physiology with special focus on membrane physiology and synaptic mechanisms
- Receptor pharmacology including receptor classifications, agonists, antagonists, development of tolerance, and analysis of receptor-ligand interactions
- Pharmacodynamics: Dose-response relationships, dose/time relationships, use of biological systems to estimate activities of drugs, statistical analysis of biological data
- Pharmacokinetics: General kinetics, absorption, distribution, elimination, metabolism, excretion and drug interactions
- Drug development methods: Animal models, preclinical development and concepts of toxicology
At the end of the course, students are expected to be able to:
- Understand concepts used in physiology and basic pharmacology.
- Calculate, estimate and discuss physiological and pharmacological parameters obtained from experimental and clinical data (pharmacodynamic and pharmacokinetic data).
- Discuss and explain pharmacology-related procedures and methods used in preclinical drug development.
- Silverthorn: Human Physiology, 6th edition, Pearson International, 2013.
- Rang, H.P., Dale, M.M., Ritter, J.M. & Flower, R. J.: Pharmacology, 7th edition, Churchill Livingstone, 2012.
- Rowland, M. & Tozer, T.N.: Clinical Pharmacokinetics and Pharmacodynamics. Concepts and Applications. 4th edition, Lippincott, Williams & Wilkins, 2011.
- Meldgaard Lund, T. and Sheykhzade M., FARMA, KU: Pharmacokinetic and -dynamic Equations and Preconditions (on the homepage).
- Sheykhzade and Pickering: Pharmacodynamic theory notes, 9th ed, 2013 (on the homepage).
• 19 hr of tutorial lessons
• 4 hours of laboratory work
• 1 project presentation (group work)
- Category
- Hours
- Class Instruction
- 38
- Exam Preparation
- 40
- Exercises
- 4
- Lectures
- 34
- Preparation
- 68
- Preparation
- 2
- Project work
- 20
- Total
- 206
- Credit
- 7,5 ECTS
- Type of assessment
- Written examination, 3 hours under invigilationProject presentations will count for 10% of the final course grade and the course examination will count for 90% of the final course grade.
Exam assessment is based on a written, closed-book exam with usually 3 or 4 different assignments, each with subparts. The individual weighting of each assignment will be clearly stated on the exam paper.
The highest number of exam points achievable is 100 and the pass requirement is 50 points. Overall impression forms part of the exam assessment and may cause the score to be adjusted by up to 10%. The adjustment is based on the demonstration of an overall understanding of basic pharmacological principles and topics and the absence of major weaknesses. - Aid
- Without aids
Apart from the standard programs and IT tools listed under The Faculty of Health and Medical Sciences at http://pc-eksamen.ku.dk/pc_exam students will at this exam also have access to MathType.
- Marking scale
- 7-point grading scale
- Censorship form
- External censorship
Criteria for exam assesment
12 - Excellent performance
A well-structured presentation with a clear outline providing exact
and correct answers. The student demonstrates a comprehensive
overview of physiology and basic pharmacology, convincingly
combining the elements learned. The student demonstrates, with few
minor weaknesses:
- A skilful command of the relevant terms, principles and methods used in physiology and pharmacology.
7 - Good performance
A coherent presentation providing understandable unambiguous
answers, the great majority of which should be correct. The student
demonstrates a reasonable overview of the elements learned. The
student demonstrates, with minor weaknesses:
- A sound knowledge of the relevant terms, principles and methods used in physiology and pharmacology.
2 - Acceptable performance
A less structured presentation with less precise answers. The
student demonstrates a limited overview and ability to combine the
elements learned. The student demonstrates, to a limited extent and
with a number of weaknesses:
- The ability to use the relevant terms, principles and methods used in physiology and pharmacology.
Course information
- Language
- English
- Course code
- SLVKB0351U
- Credit
- 7,5 ECTS
- Level
- Full Degree MasterFull Degree Master choice
- Duration
- 1 block
- Placement
- Block 1
- Schedule
- A (Tues 8-12 + Thurs 8-17)
- Course capacity
- 60 students
- Study board
- Study Board of Pharmaceutical Sciences
Contracting department
- Department of Drug Design and Pharmacology
Course responsibles
- Darryl S Pickering (6-746d676f69764477797268326f7932686f)
Lecturers
Annouced at course start.