SHUA11014U  Translational Pharmacology - From Concept to Medical Drug and from Concept to Biotech Company

Volume 2013/2014
Education
MSc Programme in Human Biology
Content

Translational pharmacology describes the process from basic pharmacological research to an approved medical drug, i.e. from idea to a pharmaceutical that can be used in therapy, including a review of the basis for setting up, funding and developing a biotech company based on drug discovery and development.

 

Learning Outcome

At the end of the course, students should be able to give an account of:

  • Drug targets – concept, discovery and validation
  • The identification of hits and leads: structure-based drug discovery
  • Optimising the medicinal chemistry and testing the properties of target molecules and of ADME properties in vitro and in vivo
  • Animal models for testing the effectiveness of medical drugs, PK, and the like
  • The development and clinical trials of pharmaceuticals
  • Setting up and funding biotech companies based on drug discovery and development – phases in the biotech company lifecycle
  • Analysis and comparisons of domestic and international biotech companies based on drug discovery and development

 

A completed Bachelor degree within the Biomedical and Natural Sciences
Lectures, assignments and case presentations in plenum
Credit
5 ECTS
Type of assessment
Oral examination
Oral presentation and discussion in course plenum of a case-story in drug-discovery or biotech company establisment and management.
Exam registration requirements
Course attestation from the course in Translational Pharmacology - From Concept to Medical Drug and from Concept to Biotech Company by participation in all aspects of the course
Aid
Only certain aids allowed

All, except for external communication devices

Marking scale
passed/not passed
Censorship form
No external censorship
More than one internal examiner
Exam period
Week 44, 2013
Criteria for exam assesment

To pass the exam the student shall be able to discuss, analyze and evaluate: 

  • Drug targets – concept, discovery and validation
  • The identification of hits and leads: structure-based drug discovery
  • Optimising the medicinal chemistry and testing the properties of target molecules and of ADME properties in vitro and in vivo
  • Animal models for testing the effectiveness of medical drugs, PK, and the like
  • The development and clinical trials of pharmaceuticals
  • Setting up and funding biotech companies based on drug discovery and development – phases in the biotech company lifecycle
  • Analysis and comparisons of domestic and international biotech companies based on drug discovery and development
  • Category
  • Hours
  • Lectures
  • 35
  • Practical exercises
  • 16
  • Preparation
  • 86
  • Exam
  • 1
  • Total
  • 138