SVEK17001U  Laboratory Animal Science Function ABD

Volume 2017/2018
Education

Molecular Biomedicine – restricted elective

Biologi bioteknologi – restricted elective. Not for the specialisation (Applied Enzymology, Bio Products) from 2016/2017

MSc Programme in Pharmaceutical Sciences - elective

MSc Programme in Medical Chemistry - elective

KA i Farmaci - valgfri

KA i Farmaceutisk videnskab – valgfri

Veterinærstuderende på alternativ differentiering

Studerende på natur- og sundhedsvidenskabelige uddannelser

 

Content

The course includes the following topics:

Legislation, ethics and welfare, comparative and basic biology, nutrition, health, genetics, housing and facilities, occupational health, pain relief incl. anaesthesia and analgesia, euthanasia, experimental design and animal models.

Learning Outcome

The course is a function A/B/D course according to the EU Directive 2010/63 /EU Article 23.2  (previously designated category C) accredited by the Federation of European Laboratory Animal Science Associations as well as the Ministry of Environment and Food under the Danish Government. 
The course gives as practical and theoretic introduction to handling, housing and using laboratory animals and how to replace, refine and reduce the use of live animals for research.

The course adheres to the more detailed learning outcomes described in the EU guidance paper 'A working document on the development of a common education and training framework to fulfill the requirements under the Directive' ( http:/​/​ec.europa.eu/​environment/​chemicals/​lab_animals/​pdf/​guidance/​education_training/​en.pdf).

After completing the course the student is expected to:

Knowledge 

  • understand that animal experimentation is complicated and requires current training to secure the well-being of the animals and the scientific outcome 
  • explain the biological basis of laboratory animal breeding and maintenance, housing and management including basic genetics and reproduction, health monitoring, housing and handling (pre-, intra and post-procedural)
  • explain the legal basis for animal experimentation 
  • explain and critically evaluate the scientific methods applied within animal experimentation including blood sampling, injections, principles for drug-development and testing, anesthesia and analgesia and evaluation of pain -and stress related behaviour in laboratory animals 
  • discuss the basic biology of laboratory animals including behavioural and physiological needs
  • explain and critically evaluate basic knowledge relating to design and evaluation of studies using live animals 

 

Skills

  • organize self-training on handling and procedures in the most common laboratory animals 
  • discuss and evaluate the basic principles on how to use animals for research 
  • discuss and evaluate principles of procedures on their future experiments 
  • discuss, evaluate and argue about the ethical basis for the use of animals for research 
     

Competencies 

  • independently take responsibility to implement and further develop practical skills in handling of common rodents used for research 
  • independently take responsibility to implement and further develop practical skills in the performance of basic animal experiments 
  • achieve a personal license to independently plan, implement and take responsibility for the design and performance of animal experimentation within the European Union according to the EU Directive 2010/63/EU Article 23.2 and the Danish executive order No 12 of 07/01/2016 §56

 

Hau, J. & Schapiro SJ: Handbook of Laboratory Animal Science, 3nd ed., Vol. 1, CRC Press, Roca Raton, 2011.

Additional review papers.

Animal experimentation legislation.

Exercise manual for Laboratory Animal Science (will be placed on Absalon).
Lectures and on-line material on Absalon

Full and satisfactory participation in practical exercises is mandatory. To be allowed for the written exam the student must perform according to the claims of the EU Guidance Paper ( http:/​/​ec.europa.eu/​environment/​chemicals/​lab_animals/​pdf/​Endorsed_E-T.pdf). If this is not the case the student will be called for follow up exercises during the course period. If performance is still not acceptable the student will without entering the practical exam be graded 'not passed'.
Basic knowledge in physiology, anatomy and pharmacology.
The theory is given as a number of online teaching modules including lectures, case work, and quizzes. Plenum discussions in a lecture room with a teacher will be offered three times during the block. The student is expected to be reading in the curriculum.

Practical exercises handling live animals with instructors are given as three mandatory sessions that the students need to sign in for. Performance will be evaluated during these exercises. The students are expected to be prepared by reading a manual and watching videos prior to the exercises sessions.

Evaluation model: Survey-based model.
Continuous feedback during the course of the semester
Credit
7,5 ECTS
Type of assessment
Written examination, 2 hours under invigilation
Written exam at Peter Bangs Vej with multiple choice, short questions and short essays.
Exam registration requirements

Full and satisfactory participation at practical exercises. Demonstration of performance for an instructor during the exercises.

Aid
Without aids
Marking scale
passed/not passed
Censorship form
No external censorship
No censorship. One internal examiner.
Exam period

At the examination week at the end of the block

Re-exam

At the examination week at the end of the subsequent block

Criteria for exam assesment

To achieve the grade passed, the student shall (in an adequate level) be able to:

Knowledge:

  • understand that animal experimentation is complicated and requires current training to secure the well-being of the animals and the scientific outcome 
  • explain the biological basis of laboratory animal breeding and maintenance, housing and management including basic genetics and reproduction, health monitoring, housing and handling (pre-, intra and post-procedural)
  • explain the legal basis for animal experimentation 
  • explain and critically evaluate the scientific methods applied within animal experimentation including blood sampling, injections, principles for drug-development and testing, anesthesia and analgesia and evaluation of pain -and stress related behaviour in laboratory animals 
  • discuss the basic biology of laboratory animals including behavioural and physiological needs
  • explain and critically evaluate basic knowledge relating to design and evaluation of studies using live animals 

 

Skills:

  • Category
  • Hours
  • E-Learning
  • 80
  • Practical exercises
  • 16
  • Colloquia
  • 20
  • Preparation
  • 88
  • Exam
  • 2
  • Total
  • 206