SHUA13014U  Translational Pharmacology - From Concept to Medical Drug and from Concept to Biotech Company

Volume 2017/2018
Education

MSc Programme in Human Biology - elective

Content

Translational pharmacology describes the process from basic pharmacological research to an approved medical drug, i.e. from idea to a pharmaceutical that can be used in therapy, including a review of the basis for setting up, funding and developing a biotech company based on drug discovery and development.

 

Learning Outcome

At the end of the course, students should be able to:

Discuss, analyze and evaluate:

  • Drug targets – concept, discovery and validation
  • The identification of hits and leads: structure-based drug discovery
  • Optimising the medicinal chemistry and testing the properties of target molecules and of ADME properties in vitro and in vivo
  • Animal models for testing the effectiveness of medical drugs, PK, and the like
  • The development and clinical trials of pharmaceuticals
  • Setting up and funding biotech companies based on drug discovery and development – phases in the biotech company lifecycle
  • Analysis and comparisons of domestic and international biotech companies based on drug discovery and development
A completed Bachelor degree within the Biomedical and Natural Sciences
Lectures, assignments and case presentations in plenum
Credit
5 ECTS
Type of assessment
Course participation
Oral presentation and discussion in course plenum of a case-story in drug-discovery or biotech company establisment and management.
Exam registration requirements

Participation in all aspects of the course

Aid
All aids allowed
Marking scale
passed/not passed
Censorship form
No external censorship
More than one internal examiner
Criteria for exam assesment

To achieve the grade Passed, the student must adequately be able to:

Discuss, analyze and evaluate: 

  • Drug targets – concept, discovery and validation
  • The identification of hits and leads: structure-based drug discovery
  • Optimising the medicinal chemistry and testing the properties of target molecules and of ADME properties in vitro and in vivo
  • Animal models for testing the effectiveness of medical drugs, PK, and the like
  • The development and clinical trials of pharmaceuticals
  • Setting up and funding biotech companies based on drug discovery and development – phases in the biotech company lifecycle
  • Analysis and comparisons of domestic and international biotech companies based on drug discovery and development
  • Category
  • Hours
  • Lectures
  • 35
  • Practical exercises
  • 16
  • Preparation
  • 84
  • Exam
  • 1
  • Total
  • 136