SBRI19015U Clinical Translational Medicine
Volume 2019/2020
Education
BRIDGE - Translational Excellence Programme
Content
- Translational research study design
- How to develop and interpret PDX models
- Automatized drug-screening in real time - for patient care
- Clinical trial design
- Communication training between patients, clinicians, basic scientist and industry
- Phase 1 studies
- First in human studies
- Discussion clinical cases including ethical issues
- Career moves from academia to industry
Learning Outcome
On completion of the course, the participants should be able to:
Knowledge
- Relate how thorough characterization (molecular, immunological, imaging) of the individual patient or patient’s samples may be used for direct selection of patient treatment/care
- Explain how information from biological experiments (in vitro and animal models) can be used as a platform for designing investigations in patients
- Discuss how biological experiments may lead to drug development
- Describe how to bring a preclinical drug to phase 1, basic requirements
- Describe Phase 1 -> 3 trials
- Plan a translational study with material from a clinical trial
- Describe different studies, non-inferior vs. superiority studies
Skills
- Integrate knowledge obtained from all other courses into translational clinical research
- Critically evaluate preclinical data - from a clinical point of view
- Generate novel ideas for clinical trials from preclinical observations
- Implement research results in clinical practice
- Solve unmet clinical needs/questions by designing the clinically relevant preclinical/ biological experiments
Competences
- Integrate basic biology into clinical knowledge
- Assess ethical considerations of how to implement new molecular tools and conduct studies with patients
- Understand the central aspects of clinical translational medicine and be able to discuss and communicate these to other scientists, clinicians, and the public
Literature
To be added
Recommended Academic Qualifications
Participants must meet the
admission criteria in BRIDGE - Translational Excellence
Programme
Teaching and learning methods
Individual projects –
presentations
Cathedral lectures
Industry visit
Patient involvement – a story from a patient
Phase 1 visit
Cathedral lectures
Industry visit
Patient involvement – a story from a patient
Phase 1 visit
Workload
- Category
- Hours
- Course Preparation
- 5
- Excursions
- 4
- Lectures
- 22
- Practical Training
- 6
- Project work
- 5
- Total
- 42
Feedback form
Oral
Continuous feedback during the course of the
semester
Sign up
Automatic registration upon appointment in the Translational Excellence Programme
Exam (Clinical Translational Medicine)
- Credit
- 0 ECTS
- Type of assessment
- Continuous assessmentCourse participationAttendance and active participation
- Exam registration requirements
Participants are automatically registered for the Examination upon course registration.
- Aid
- All aids allowed
- Marking scale
- passed/not passed
- Censorship form
- No external censorship
Criteria for exam assesment
Knowledge
- Relate how thorough characterization (molecular, immunological, imaging) of the individual patient or patient’s samples may be used for direct selection of patient treatment/care
- Explain how information from biological experiments (in vitro and animal models) can be used as a platform for designing investigations in patients
- Discuss how biological experiments may lead to drug development
- Describe how to bring a preclinical drug to phase 1, basic requirements
- Describe Phase 1 -> 3 trials
- Plan a translational study with material from a clinical trial
- Describe different studies, non-inferior vs. superiority studies
Skills
- Integrate knowledge obtained from all other courses into translational clinical research
- Critically evaluate preclinical data - from a clinical point of view
- Generate novel ideas for clinical trials from preclinical observations
- Implement research results in clinical practice
- Solve unmet clinical needs/questions by designing the clinically relevant preclinical/ biological experiments
Competences
- Integrate basic biology into clinical knowledge
- Assess ethical considerations of how to implement new molecular tools and conduct studies with patients
- Understand the central aspects of clinical translational medicine and be able to discuss and communicate these to other scientists, clinicians, and the public
Course information
- Language
- English
- Course code
- SBRI19015U
- Credit
- 0 ECTS
- Level
- Part Time MasterPh.D.
- Duration
- Placement
- Spring
- Schedule
- See course dates and course programme in Absalon
- Course capacity
- 15 participants
- Continuing and further education
- Study board
- Study Board for the Professionel Master´s Degree Programmes at The Faculty og Health and Medical Science
Contracting department
- Department of Clinical Medicine
Contracting faculty
- Faculty of Health and Medical Sciences
Course Coordinators
- Kirsten Grønbæk (17-6d6b74757667703069747167706463676d4264746b65306d7730666d)
Saved on the
19-09-2019