SBIK10168U  Immunology

Volume 2017/2018
Education

MSc Programme in Biology-Biotechnology - compulsory

Content

The theoretical part will cover modern immunology, with special emphasis on the current research areas of interest to the biotech industry.
The course will cover the basic principles of the immune system and its regulation and give an updated insight into modern molecular immunology.

The practical course will focus on modern immunological techniques, which apart from basic techniques, will include cultivation and purification of lymphocytes from blood, flow cytometry and molecular signaltransduction techniques.

Learning Outcome

The objective is to provide the student with an updated knowledge about immunology and the immune system.
The course will cover key elements in the development, activation and regulation of the innate and adaptive immunune system.
In the end of the course we will focus on diseases caused by lack immune regulation. This will include Allergy, Autoimminity and Cancer and the current/future treatment strategies.

The practical course will cover a variety of currently used molecular cellular immunological-techniques, which can also be used in non-immunological research. The practical course will also include critical reading and discussion of original research articles.

Knowledge:
- Describe the cells and structural building of the immune system.
- Understand how the Innate immune system works, including creation of inflammation and specific ways of patogen recognition and phagocytosis.
- Understand the basic principles that controls adaptive immunity, including development of antigen specific receptors (TCR and BCR), nature and function of MHC molecules, activation and regulation of T and B cells, development of immunological memory.
- Insight in the molecular signal regulation of immunity, including cytokines and intracellular signal mechanisms.
- Describe the function of the immune system during, autoimmunity, allergy, immune defects, transplantation and cancer.
- Perform immunological experiments, including critical evaluation of the results.

Skills:
Use immunologically founded reasoning on various scientific problems concerning health and related issues.
Use various immunologically and molecular techniques to solve questions raised in immunology and related fields.

Competences:
Have acquired knowledge to discuss immunological literature, immunological problems, techniques and an updated knowledge of molecular immunology - both basic and more specialised areas.
Have a technical foundation to suggest experimental analysis of some immunological questions.

Janeway's Immunobiology, 9th edition.

Manuals for practical course in Immunology.

Competencies corresponding to SBIB10125U Cell Biology.
Lectures, problem solving, practical laboratory course (nine days incl. report writing).
Credit
15 ECTS
Type of assessment
Written examination, 4 hours under invigilation
4h written exam without books. The grade is based on an overall assessment of the answers.
Exam registration requirements

Approved practical course and at least 80 % attendance in practical part.
Submission of reports.

Aid
Without aids
Marking scale
7-point grading scale
Censorship form
No external censorship
More than one internal examiner
Re-exam

If the requirement of approved practical course and at least 80 % attendance in practical part of the course is not fulfilled, the student must take the course again the next year.

Criteria for exam assesment

See learning outcome

  • Category
  • Hours
  • Lectures
  • 32
  • Theory exercises
  • 48
  • Practical exercises
  • 68
  • Preparation
  • 260
  • Exam
  • 4
  • Total
  • 412