NBIK13017U Molecular Biotechnology
MSc Programme in Biology
MSc Programme in Biochemistry
The theoretical part includes:
- A thorough review of organisms used for recombinant protein production
- Protein purification related to recombinant protein production.
- Quality control of recombinant proteins
- Protein quality in relation to application
- Optimization of recombinant protein production
- Large scale growth of host organism
- Industrial recombinant protein production with experts from Industry
Knowledge:
Molecular Biotechnology focuses on how to apply a thorough
knowledge on fundamental molecular biology, genetics and protein
chemistry to rationalize recombinant protein production on a lab
scale as well as on an industrial scale. The student will gain in
depth knowledge on the organisms used in industry for recombinant
protein production. This will include bacteria, eukaryotic
microorganisms and mammalian cell lines as well as intact
organisms. The student will obtain knowledge to select the most
optimal host cell for production of a specific protein.
Skills:
The student gains core competences within recombinant protein
production as an important tool in the research laboratory and a
billion dollar business for the biotech industry. A number of
different cell factories are available for recombinant protein
production. The degree of confidence with recombinant protein
production obtained during the course allows the student to
evaluate benefits and draw backs related to selection of host
organism and protein purification. The student will get familiar
with how to optimize recombinant protein production by applying
methods from molecular biology, genetics and protein science. The
student will be able to critically evaluate the potential of a
specific host organism in relation to the intended application of
the recombinant protein.
Competences:
The competences obtained by the student include
to interpret and evaluate data from the scientific literature related to recombinant protein production
to design recombinant protein production and purification experiments
to select an expression host compatible with desired quality of the recombinant protein product
to evaluate possibilities for setting up recombinant protein production on a laboratory and industrial scale
to make a literature study on a subject related to recombinant protein production and make an oral presentation of the outcome.
See Absalon
The course is offered to students of Biology, Biochemistry, Molecular Biomedicine, Nanotechnology, Sports Science and related educations.
- Category
- Hours
- Colloquia
- 28
- Lectures
- 28
- Preparation
- 150
- Total
- 206
As
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Continuing Education - click here!
- Credit
- 7,5 ECTS
- Type of assessment
- Written assignment, 1 weekWritten take-home assignment, 1 week.
- Exam registration requirements
The student must make an oral presentation in class. The presentation is 30 minutes long and can be made in groups of two.
- Marking scale
- 7-point grading scale
- Censorship form
- No external censorship
One internal examiner
- Re-exam
If the student has not fulfilled the exam registration requirements the student must hand in a written assignment to the teacher no later that two weeks before the reexam. The teacher decides the topic of the assignment and the assingment must be approved.
Criteria for exam assesment
To pass the student should
- Be able to give a detailed description of and evaluate the host organisms presented during the course for recombinant protein production.
- Be able to thoroughly evaluate experimental data from the scientific literature
- Be able to thoroughly present data from the scientific literature on recombinant protein production
Course information
- Language
- English
- Course code
- NBIK13017U
- Credit
- 7,5 ECTS
- Level
- Full Degree Master
- Duration
- 1 block
- Placement
- Block 4
- Schedule
- A
- Course capacity
- 40
- Continuing and further education
- Study board
- Study Board of Biomolecular Sciences and Technology
Contracting department
- Department of Biology
Course responsibles
- Per Amstrup Pedersen (10-7667766b6a6b78796b7446686f7534717b346a71)
Lecturers
Teachers from Department of Biology and Industry