NSCPHD1101 PhD course in analyses of genotyping and next-generation sequencing data in medical and population genetics
PLEASE NOTE
The PhD course database is under construction. If you want to sign up for this course, please click on the link in order to be re-directed. Link: https://phdcourses.ku.dk/nat.aspx
The course is a comprehensive introduction to a number of topics and common research tools used in analyses of genetic data. Topics include: genetic drift, natural selection, population structure, Fst, linkage disequilibrium, relatedness, association mapping, GWAS, IBD mapping, admixture mapping, genotyping data, next-generation sequencing (NGS) data, 1000 genomes project data. The main focus will be on humans but the methods are applicable for many other species as well. Lectures will be combined with hands-on computer exercises mostly using R and commandline based programs.
After the course the student will be able to
- Use population genetic theory to infer basic population genetics characteristics from genetic data, including Fst, population size, relatedness and linkage disequilibrium
- Be able to infer ancestry and population structure based on genetic data
- Select the optimal strategy for disease mapping based on the available data, the trait of interest, and the population genetics characteristics of the sample population, including taking population structure into account
- Perform disease mapping, including genome-wide association studies
- Interpret and discuss the results of own analyses and results in the scientific literature
Notes and articles for background reading prior to course start will be made available on the course webpage (password protected).
Additionally, handouts will be passed out during the course, but for each lecture there is one or two articles/notes that should be read in advance.
- Category
- Hours
- Exam
- 60
- Exercises
- 20
- Lectures
- 20
- Preparation
- 80
- Total
- 180
Master students can sign up via KUnet. Everyone else via e-mail.
- Credit
- 5 ECTS
- Type of assessment
- Course participation
- Aid
- All aids allowed
- Marking scale
- passed/not passed
- Censorship form
- No external censorship
- Credit
- 7,5 ECTS
- Type of assessment
- Written assignment
- Exam registration requirements
Active attendance withing the first week of the course
- Aid
- All aids allowed
- Marking scale
- passed/not passed
- Censorship form
- No external censorship
- Exam period
Week 35
Course information
- Language
- English
- Course code
- NSCPHD1101
- Credit
- See exam description
- Level
- Ph.D.
- Duration
- The course is a 1 week full time course.
- Placement
- Summer
Lectures and exercises run from August 22 to August 26 2016
- Schedule
- It is a full time one week long course
- Course capacity
- 40 students (PhD student will have first priority)
- Study board
- Natural Sciences PhD Committee
Contracting department
- Department of Biology
Course responsibles
- Ida Moltke (3-6e696645676e7433707a336970)
- Anders Albrechtsen (12-656570667669676c7877697244666d73326f7932686f)
Lecturers
Assistant professor Ida Moltke, University of Copenhagen
Associate professor Anders Albrechtsen, University of Copenhagen
Guest lectures by several international leaders in the field