SVEK13010U Biomedicine
The course includes modules of laboratory animal science,
experimental design, in vivo pharmacology, gentics and toxicology
and histopathology as well as a range of laboratory methods
complementing in vivo experiments. In parallel, theoretical and
practical aspects of pro- and eukaryote genomics are introduced
including molecular biological methods used for research within
these areas. Other topics covered are modern diagnostic methods,
typing methods, molecular methods and strategies for studies of
host pathogen interaction, evolution of pathogens, vaccinology, and
the immune system in relation to infections and inflammatory
diseases.
The laboratory animal science part of the course has been
accredited by the Danish Ministry of Food, agriculture and
fisheries and by the Federation of European Laboratory Animal
Associations (FELASA) as adequate for researchers acquiring a
license to perform animal experiments.
The aim of the course is to provide the students with
work-relevant competences and qualifications required in the broad
field of biomedical research. This includes qualifications to
manage a housing facility for experimental animals and to design,
perform and evaluate laboratory animal experiments in biomedical
research and product development. Moreover, it provides the
students with a thorough knowledge on methodologies of mammalian
genomics, clinical microbiology, parasitology, genetics and
clinical as well as molecular pathology and the role of these
subjects when applied in drug – and vaccine development.
Learning outcomes
Knowledge
Describe modern diagnostic methods and principles; summarize rules and regulations, principles, methods and terminology relevant for the planning, execution and evaluation of experimental animal research projects and regulatory toxicity testing
Describe various animal models for human diseases presented in the course
Describe principles of housing, breeding and use of laboratory animals
Describe basic procedures and practical methodologies in Laboratory Animal Science, experimental surgery and in vivo pharmacology
Describe inference methods and risk analysis
Describe mechanisms of antibiotic and anthelmintic resistance and host interaction and reflect on the clinical health relevance.
Describe the principles of vaccine development and effects of use of vaccines.
Describe methods and strategies commonly used to determine virulence factors.
Describe the structure and function of the mammalian and prokaryote genome; summarize the main issues in relation to genetic mapping of qualitative and quantitative traits.
Describe various genetic technologies using in biomedical research
Describe and perform main molecular biological methods.
Understand and provide a critical evaluation of literature describing subjects within the area of biomedicine
Skills
Explain and assess strengths and weaknesses of commonly used laboratory methods in clinical microbiology, parasitology and pathology
Evaluate the use of in vitro and in vivo methodology in research and development
Explain basic ethical theories on use of animals in research and on animal welfare, including the 3 Rs
Use basic statistical and inference methods.
Evaluate histological lesions and reactions in laboratory animals.
Use basic surgical methods in laboratory animal science
Explain how to address and/or counteract common causes of misclassification in clinical microbiological, parasitological and pathological tests
Design a quality assurance program for diagnostic procedures
Determine antibiotic resistance both by quantitative and qualitative methods including specialized procedures
Evaluate which molecular genetic techniques are relevant for the study of a given genetic problem
Analyse, evaluate and present results from simple diagnostic tests in mammals
Explain the basic methodologies and principles demonstrated and practiced at the practical exercise during the course work
Competences
Work independently with problem solving, diagnosing and presenting relevant findings in clinical microbiology, clinical pathology and In vivo pharmacology.
Be able to identify virulence factors of microorganisms and parasites
Use knowledge on virulence factors in development of methods to control infections, e.g. in the form of active and passive immunizations and new drugs
Be able to work independently with basic genetic laboratory procedures
Discuss the ethical use of animals and in vitro methods in research and product development
Discuss strength and weaknesses of common animals models including genetically modified models
Be able to design, execute, evaluate and manage experimental animal research projects
Use theoretical and practical methodology in laboratory experiments employing live animals
Critically evaluate experimental designs and stated outcomes
Use acquired knowledge to assess novel problems or problem areas and confidently apply knowledge-based suggestions for solutions
Be able to find new information/literature on topics within the area of biomedicine
Be able to take responsibility for own professional development and specialization.
Be able to confident and competent present, communicate and discuss scientific research results
Selected textbooks.
An updated list of carefully selected, recommendable textbooks, relevant material and suggested further readings will be posted on Absalon in due time before course start
SVEK13003U Veterinary Imaging
SVEK13002U Akutmedicin, obstetrik, intensiv terapi og klinisk anæstesiologi
SVEK13007U Almen klinisk praksis familiedyr
SVEK13008U Almen klinisk praksis, store husdyr
SVEK13006U Praktisk besætningsrådgivning og kødkontrol
SVEK13001U Veterinary Paraclinics
Passed the following courses:
Medicin, kirurgi og reproduktion - mindre og store husdyr SVEK13005 og SVEK13004.
- Category
- Hours
- E-Learning
- 20
- Exam
- 1
- Guidance
- 30
- Lectures
- 134
- Practical exercises
- 300
- Preparation
- 160
- Project work
- 62
- Theory exercises
- 22
- Total
- 729
- Credit
- 26,5 ECTS
- Type of assessment
- Oral examination, 30 minutesOral examination in practical and theoretical skills and oral presentation of a poster prepared on the basis of experimental data obtained during the course.
Passing the exam in experimental animal sciences provides FELASA authorisation category ‘C’. - Exam registration requirements
- 80 % attendance to practicals involving live animals is
required to attend the FELASA category C in Laboratory Animal
Science exam during the course programme. Passing the FELASA
category C exam is required in order to obtain FELASA-accredited
course certificate.
80 % attendance to practicals involving live animals in exercise module II is required to attend the Biomedicine examination at the end of the course.
Students,who has not passed the FELASA category C exam prior to the Biomedicine examination may attend a re-examination in connection to the biomedicine examination.
Both, FELASA-accredited course certificate and a passed Biomedicine examination are required to pass the course. - Aid
- Without aids
- Marking scale
- 7-point grading scale
- Censorship form
- External censorship
Criteria for exam assesment
The student must show convincing, confident and competent
compliance with all stated learning outcomes:
Knowledge
Describe modern diagnostic methods and principles; summarize rules and regulations, principles, methods and terminology relevant for the planning, execution and evaluation of experimental animal research projects and regulatory toxicity testing
Describe various animal models for human diseases presented in the course
Describe principles of housing, breeding and use of laboratory animals
Describe basic procedures and practical methodologies in Laboratory Animal Science, experimental surgery and in vivo pharmacology
Describe inference methods and risk analysis
Describe mechanisms of antibiotic and anthelmintic resistance and host interaction and reflect on the clinical health relevance.
Describe the principles of vaccine development and effects of use of vaccines.
Describe methods and strategies commonly used to determine virulence factors.
Describe the structure and function of the mammalian and prokaryote genome; summarize the main issues in relation to genetic mapping of qualitative and quantitative traits.
Describe various genetic technologies using in biomedical research
Describe and perform main molecular biological methods.
Understand and provide a critical evaluation of literature describing subjects within the area of biomedicine
Skills
Explain and assess strengths and weaknesses of commonly used laboratory methods in clinical microbiology, parasitology and pathology
Evaluate the use of in vitro and in vivo methodology in research and development
Explain basic ethical theories on use of animals in research and on animal welfare, including the 3 Rs
Use basic statistical and inference methods.
Evaluate histological lesions and reactions in laboratory animals.
Use basic surgical methods in laboratory animal science
Explain how to address and/or counteract common causes of misclassification in clinical microbiological, parasitological and pathological tests
Design a quality assurance program for diagnostic procedures
Determine antibiotic resistance both by quantitative and qualitative methods including specialized procedures
Evaluate which molecular genetic techniques are relevant for the study of a given genetic problem
Analyse, evaluate and present results from simple diagnostic tests in mammals
Explain the basic methodologies and principles demonstrated and practiced at the practical exercise during the course work
Competences
Work independently with problem solving, diagnosing and presenting relevant findings in clinical microbiology, clinical pathology and In vivo pharmacology.
Be able to identify virulence factors of microorganisms and parasites
Use knowledge on virulence factors in development of methods to control infections, e.g. in the form of active and passive immunizations and new drugs
Be able to work independently with basic genetic laboratory procedures
Discuss the ethical use of animals and in vitro methods in research and product development
Discuss strength and weaknesses of common animals models including genetically modified models
Be able to design, execute, evaluate and manage experimental animal research projects
Use theoretical and practical methodology in laboratory experiments employing live animals
Critically evaluate experimental designs and stated outcomes
Use acquired knowledge to assess novel problems or problem areas and confidently apply knowledge-based suggestions for solutions
Be able to find new information/literature on topics within the area of biomedicine
Be able to take responsibility for own professional development and specialization.
Be able to confident and competent present, communicate and discuss scientific research results
Course information
- Language
- English
- Course code
- SVEK13010U
- Credit
- 26,5 ECTS
- Level
- Full Degree Master
- Duration
- 1 semester
- Placement
- Block 3 And Block 4
Final schedule for the course will be listed on Absalon two weeks prior to course start
- Schedule
- 9 uger i blok 3 og første 8 uger i blok 4.
- Course capacity
- 36 participants. Forbeholdt veterinærstuderende.
- Study board
- Study Board of Veterinary Sciences
Contracting departments
- Department of Veterinary Disease Biology
- Department of Public Health
- Department of Veterinary Clinical and Animal Sciences
Course responsibles
- Dorte Bratbo Sørensen (4-738372855184867f753f7c863f757c)
Chief responsibility - Jens Lykkesfeldt (4-7b80817d5184867f753f7c863f757c)
Pharmacology/In vivo pharmacology - Merete Fredholm (2-7c754f82847d733d7a843d737a)
Genetics - Anders Miki Bojesen (4-7e7a7c7a5184867f753f7c863f757c)
Microbiology
Lecturers
Undervisere fra de tre institutter samt indbudte gæsteforelæsere