NSCPHD1264 Functional Protein Dynamics

Volume 2014/2015
Education
Biochemistry
Biology
Molecular Biomedicine
Content

This summer school focuses on functional dynamics in proteins occurring on timescales ranging from picoseconds to hours as well as their relation to protein function. Recent innovations in experimental biophysics, including NMR, single molecule studies, X-ray and neutron scattering, and mass spectrometry have pushed the limits for biological studies and it is now possible to investigate dynamic processes on timescales and at a resolution that were previously inaccessible. Together with these developments, computational tools have now matured to a level where they can be used both to predict protein properties and help interpret experiments at the atomic level. Importantly, this synergy between experiments and simulations creates novel, exciting avenues to study the fundamental dynamics that drive protein folding, protein-ligand interactions and allosteric regulation of proteins.


Confirmed speakers:

  • Wolfgang Peti, Brown University
  • Mikael Akke, Lund University
  • Ben Schuler, University of Zürich
  • Frans Mulder, University of Aarhus
  • Jan H Jensen, University of Copenhagen
  • Thomas Hamelryck, University of Copenhagen
  • Kasper D Rand, University of Copenhagen
  • Lise Arleth, University of Copenhagen
  • Lene Oddershede, University of Copenhagen
  • Kresten Lindorff-Larsen, University of Copenhagen
  • Kaare Teilum, University of Copenhagen
  • Birthe B Kragelund, University of Copenhagen

 

Learning Outcome

The participants will gain insight into state-of-the art of the field of protein dynamics.

The course material, i.e. papers for the round-table discussions is available on the course homepage: http:/​/​www1.bio.ku.dk/​english/​research/​pv/​sbin_lab/​pss/​summer-school-2014/​

The school will offer 12 lectures and 12 round table discussions chaired by the invited lecturers. The students are required to be active participants in the round table discussions. The teachers will provide the students with literature etc for their preparation for the round table discussions.
  • Category
  • Hours
  • Class Instruction
  • 18
  • Class Seminar
  • 8
  • Colloquia
  • 8
  • Preparation
  • 85
  • Study Groups
  • 6
  • Total
  • 125
Credit
5 ECTS
Type of assessment
Course participation under invigilation
Oral examination, 15 min under invigilation
The student participants will present an obligatory oral presentation of their Ph. D. projects and a brief written abstract. In addition the students are expected to participate actively in the teaching and roundtable paper discussions.
Marking scale
completed/not completed
Censorship form
No external censorship
Criteria for exam assesment

The students must demonstrate an understanding of the problems being discussed in the round table paper discussions and be able to present their projects in a comprehensible and coherent manner.