NSCPHD1180 Advanced Chromatography and Mass Spectrometry
Advanced course in chromatography and mass spectrometry for chemical analysis of organic compounds. This course is a natural extension of any basic course in analytical chemistry for everybody who is going to use modern hyphenated techniques such as GC-MS, LC-MS(MS) for analysis of complex mixtures. The course covers chromatographic separation of organic compounds with special emphasize on the molecular mechanism and theory of analyte-column interactions for liquid and gas chromatography, and the theory of ionization, fragmentation, mass separation, detection and data-analysis for all kind of mass spectrometers and ionization techniques in common use coupled to gas chromatography, liquid chromatography and capillary electrophoresis. All common analytical instruments and techniques from GC-FID/MS to UPLC-UV/FLU/MSMS are addressed. The theory is supplemented with computer simulations and hands-on experiments and expert guest-lectures of selected topics.
"Introduction to Modern Liquid Chromatography", by Lloyd R. Snyder, Douglas Kirkland and John W. Dolan, Wiley 2009, and "Mass Spectrometry. Principles and Applications", by Edmond de Hoffmann and Vincent Stroobant, 3rd Ed., Wiley 2007. "High-Performance Gradient Elution. The Practical Application of the Linear-Solvent-Strength Model", by Lloyd R. Snyder and John W. Dolan, Wiley 2007 and “Interpretation of Mass Spectra”, by Fred W. McLafferty and Frantisek Turecek, University Science Books 1993 will be used to some extend. Furthermore, selected articles will be included.
For questions feel free to contact Nikoline Juul Nielsen or Bo Svensmark.
- Category
- Hours
- Exam
- 10
- Lectures
- 48
- Practical exercises
- 16
- Preparation
- 120
- Theory exercises
- 16
- Total
- 210
- Credit
- 7,5 ECTS
- Type of assessment
- Oral examinationStudent presentations of curriculum are mandatory.
- Exam registration requirements
- 4 ECTS is given if students follew the course in either Chromatography only or Mass Spectrometry only.
Course information
- Language
- English
- Course code
- NSCPHD1180
- Credit
- 7,5 ECTS
- Level
- Ph.D.
- Placement
- Block 2
- Schedule
- AAll Tuesdays and some Thursdays at Campus Frederiksberg. Full day sessions on Thursdays will sometimes be conducted at other research institutions or with industry in the Copenhagen area. If outside Copenhagen area transportation will be organised.
- Course capacity
- Maximum 30 participants. This is the total sum of student allowed from this course or from the master course Advanced Analytical Chemistry – Chromatography and Mass Spectrometry.
- Price
For participants from Danish Universities teaching is free of charge. External students are charged 3000 dkr for the teaching.
All PhD students (including those from Danish Universities) are charged for instrument-time, laboratory expenses and expenses related to excursions amounting to a total of 5000 dkr for the full course (7.5 ECTS), and 3000 dkr for each of the separate parts: Chromatography alone (4 ECTS) or Mass Spectrometry alone (4 ECTS).- Study board
- Natural Sciences PhD Committee
Contracting department
- Department of Plant and Environmental Sciences
Course responsibles
- Nikoline Juul Nielsen (3-7e7a7e50807c757e3e7b853e747b)
- Bo Svensmark (9-76796871767064756e43736f6871316e7831676e)
Lecturers
Several, but none confirmed yet.